| Name | Pos | Salary | Through | Years Left | Note | Years in Majors |
| J. Giambi | 1B | $13,125,000 | 2008 | 1 years left | Free agent after this season! | 13 years |
| S. Loux | SP | $9,500,000 | 2013 | 6 years left | | 6 years |
| T. Nixon | RF | $9,250,000 | 2008 | 1 years left | Free agent after this season! | 12 years |
| N. Garciaparra | SS | $8,350,000 | 2009 | 2 years left | | 12 years |
| J. Lopez | C | $6,000,000 | 2008 | 1 years left | Free agent after this season! | 16 years |
| M. Lowell | 3B | $5,200,000 | 2009 | 2 years left | | 11 years |
| B. Huskey | LF | $5,000,000 | 2009 | 2 years left | | 13 years |
| C. Nitkowski | SP | $4,800,000 | 2008 | 1 years left | Free agent after this season! | 11 years |
| T. Walker | 2B | $4,250,000 | 2010 | 3 years left | | 12 years |
| M. Crudale | MR | $3,750,000 | 2008 | 1 years left | Free agent after this season! | 8 years |
| H. Kuroda | SP | $3,250,000 | 2010 | 3 years left | | 5 years |
| J. Liefer | LF | $2,750,000 | 2009 | 2 years left | | 8 years |
| J. Patterson | SP | $2,450,000 | 2010 | 3 years left | | 6 years |
| B. Jenks | CL | $2,442,857 | 2008 | 1 years left | Arbitration (Estimate: $2,750,000) | 3 years |
| K. Lohse | SP | $2,290,000 | 2010 | 3 years left | | 6 years |
| R. Fick | LF | $2,125,000 | 2009 | 2 years left | | 9 years |
| C. Woodward | 2B | $1,750,000 | 2010 | 3 years left | | 6 years |
| M. Ellis | SS | $1,750,000 | 2010 | 3 years left | | 6 years |
| B. Chen | MR | $914,286 | 2008 | 1 years left | Free agent after this season! | 5 years |
| S. Victorino | CF | $828,571 | 2008 | 1 years left | Arbitration (Estimate: $1,040,000) | 4 years |
| D. Brown | LF | $820,000 | 2010 | 3 years left | | 6 years |
| C. Paronto | MR | $731,429 | 2008 | 1 years left | Free agent after this season! | 5 years |
| J. Closser | C | $350,000 | 2008 | 1 years left | Arbitration (Estimate: $300,000) | 4 years |
| J. Powell | MR | $300,000 | 2008 | 1 years left | Arbitration (Estimate: $300,000) | 2 years |
| D. Sadler | 3B | $300,000 | 2008 | 1 years left | Arbitration (Estimate: $300,000) | 3 years |
| J. Standridge | MR | $300,000 | 2008 | 1 years left | Arbitration (Estimate: $690,000) | 2 years |
| M. Lindstrom | MR | $300,000 | 2008 | 1 years left | Automatic Resign. | 1 years |
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